| Year | Award | Category | Nominee(s) | Result |
|---|---|---|---|---|
| 2013 | 3rd Critics’ Choice Television Awards | Best Actress in a Drama Series | Tatiana Maslany | Won |
| Television Critics Association Award | Individual Achievement in Drama | |||
| Outstanding New Program | Orphan Black | Nominated | ||
| Young Hollywood Awards | Breakthrough Performance—Female | Tatiana Maslany | Won | |
| EWwy Award | Best Actress in a Drama Series | |||
| Best Drama Series | Orphan Black | |||
| Tubey Award | Most Underrated Show | |||
| Best New Show | ||||
| 2014 | Satellite Award | Best Television Series or Miniseries, Genre | Nominated | |
| Best Actress in a Drama Series | Tatiana Maslany | |||
| People’s Choice Award | Favorite Sci-Fi/Fantasy Actress | |||
| Golden Globe Award | Best Performance in a Television Series – Drama Actress | |||
| 2nd Canadian Screen Awards | Shaw Media Award for Best Performance by an Actress in a Continuing Leading Dramatic Role | Won | ||
| Shaw Media Award for Best Dramatic Series | Orphan Black | |||
| Best Costume Design | “Instinct” | Nominated | ||
| Best Direction in a Dramatic Series | “Endless Forms Most Beautiful” | Won | ||
| Best Photography in a Dramatic Program or Series | ||||
| Best Writing in a Dramatic Series | “Natural Selection” | |||
| “Unconscious Selection” | Nominated | |||
| Best Picture Editing in a Dramatic Program or Series | Won | |||
| Best Production Design or Art Direction in a Fiction Program or Series | “Conditions of Existence” | |||
| Best Performance by an Actor in a Featured Supporting Role in a Dramatic Program or Series | Michael Mando | Nominated | ||
| Kevin Hanchard | ||||
| Jordan Gavaris | Won | |||
| Best Performance by an Actress in a Featured Supporting Role in a Dramatic Program or Series | Maria Doyle Kennedy | |||
| Best Performance in a Guest Role, Dramatic Series | Natalie Lisinska | |||
| Peabody Awards | Peabody Award | Orphan Black | ||
| GLAAD Media Award | Outstanding Drama Series | Orphan Black | Nominated | |
| Gracie Award | Outstanding Female Actor in a Breakthrough Role | Tatiana Maslany | Won | |
| Writers Guild of Canada Award | Drama Series | “Variations Under Domestication” | ||
| “Unconscious Selection” | Nominated | |||
| “Parts Developed in an Unusual Manner” | ||||
| Canadian Cinema Editors Award | Best Editing in Long Form Television Series | Variation Under Nature | Won | |
| “Unconscious Selection” | Nominated | |||
| 4th Critics’ Choice Television Awards | Best Lead Actress in a Drama Series | Tatiana Maslany | Won | |
| Television Critics Association Award | Individual Achievement in Drama | Tatiana Maslany | Nominated | |
| Constellation Award | Best Male Performance in a 2013 Science Fiction Television Episode | Jordan Gavaris | Won | |
| Best Female Performance in a 2013 Science Fiction Television Episode | Tatiana Maslany | |||
| Outstanding Canadian Contribution to Science Fiction Film or Television in 2013 | ||||
| Best Science Fiction Television Series of 2013 | Orphan Black | |||
| Best Overall 2013 Science Fiction Film or Television Script | “Variations Under Domestication” | Nominated | ||
| EWwy Award | Best Actress in a Drama Series | Tatiana Maslany | Won | |
| Best Supporting Actor in a Drama Series | Jordan Gavaris | |||
| Hugo Award | Hugo Award for Best Dramatic Presentation, Short Form | “Variations Under Domestication” | Nominated | |
| Directors Guild of Canada | Best Direction TV Series | John Fawcett | Won | |
| Best Drama TV Series | Orphan Black | |||
| Best Picture Editing | Stephen Lawrence | |||
| 2015 | Screen Actors Guild Award | Outstanding Performance by a Female Actor in a Drama Series | Tatiana Maslany | Nominated |
| 3rd Canadian Screen Awards | ||||
| Shaw Media Award for Best Dramatic Series | Orphan Black | Won | ||
| Best Direction in a Drama Series | TJ Scott – “Mingling Its Own Nature With It” | |||
| Best Original Music Score for a Series | Trevor Yuile – “By Means Which Have Never Yet Been Tried” | |||
| Best Photography in a Dramatic Program or Series | Aaron Morton – “By Means Which Have Never Yet Been Tried” | |||
| Best Picture Editing in a Dramatic Program or Series | D. Gillian Truster – “Governed as It Were By Chance” | |||
| Best Production Design or Art Direction in a Fiction Program or Series | Liz Calderhead, John Dondertman – “Things Which Have Never Yet Been Done” | |||
| Best Sound in a Dramatic Program or Series | Tom Bjelic, Hervig Gayer, John Laing, Dale Lennon, Rudy Michael, Stephan Traub, Marilee Yorston – “By Means Which Have Never Yet Been Tried” | Nominated | ||
| Best Visual Effects | Anthony DeChellis, Eric Doiron, Nathan Larouche, Lon Molnar, Geoff D.E. Scott, Sarah Wormsbecher – “By Means Which Have Never Yet Been Tried” | |||
| Best Writing in a Dramatic Series | Graeme Manson – “By Means Which Have Never Yet Been Tried” | Won | ||
| Graeme Manson, Karen Walton – “Governed by Sound Reason and True Religion” | Nominated | |||
| Best Achievement in Casting | Sharon Forrest, Susan Forrest – “Governed by Sound Reason and True Religion” | Won | ||
| Shaw Media Award for Best Performance by an Actress in a Continuing Leading Dramatic Role | Tatiana Maslany – “By Means Which Have Never Yet Been Tried” | |||
| Best Performance by an Actor in a Featured Supporting Role in a Dramatic Program or Series | Jordan Gavaris – “Mingling Its Own Nature With It” | |||
| GLAAD Media Award | Outstanding Drama Series | Orphan Black | Nominated | |
| Hugo Award | Hugo Award for Best Dramatic Presentation, Short Form | “By Means Which Have Never Yet Been Tried” | Won | |
| EWwy Awards | Ewwy Award for Best Supporting Actor — Drama | Jordan Gavaris | Nominated | |
| 67th Primetime Emmy Awards | Outstanding Lead Actress in a Drama Series | Tatiana Maslany | ||
| Directors Guild of Canada | Best Direction TV Series | John Fawcett | ||
| Helen Shaver | ||||
| Best Drama TV Series | Orphan Black | Won | ||
| Best Picture Editing | Jay Prychidny | Nominated | ||
| 2016 | 4th Canadian Screen Awards | Best Performance by an Actor in a Continuing Leading Dramatic Role | Ari Millen | Won |
| Best Performance by an Actress in a Continuing Leading Dramatic Role | Tatiana Maslany | |||
| Best Performance by an Actress in a Featured Supporting Role in a Dramatic Program or Series | Maria Doyle Kennedy | Nominated | ||
| Best Achievement in Makeup | Stephen Lynch, Sandy Sokolowski | Won | ||
| Best Photography in a Dramatic Program or Series | Aaron Morton – “Certain Agony of the Battlefield” | |||
| Best Picture Editing in a Dramatic Program or Series | Matthew Anas – “Newer Elements of Our Defense” | |||
| Jay Prychidny, “Certain Agony of the Battlefield” | Nominated | |||
| Best Sound in a Dramatic Program or Series | Christopher Guglick, John Laing, Mark Gingras, Herwig Gayer, Orest Sushko, and Marilee Yorsten – “History Yet to Be Written” | |||
| Best Visual Effects | Geoff D.E. Scott, Sarah Wormsbecher, Lon Molnar, Eric Doiron, Nathan Larouche, Anthony DeChellis, Joel Chambers, Jason Snea, Kaiser Thomas and Jawahar Bhatti – “History Yet to Be Written” | |||
| Best Direction in a Dramatic Series | Helen Shaver – “Certain Agony of the Battlefield” | |||
| Best Original Music Score for a Series | Trevor Yuile – “Certain Agony of the Battlefield” | Won | ||
| Best Writing in a Dramatic Series | Alex Levine – “Scarred by Many Past Frustrations” | |||
| Graeme Manson – “The Weight of This Combination” | Nominated | |||
| Prix Aurora Awards | Best Visual Presentation | Orphan Black | Won | |
| 68th Primetime Emmy Awards | Outstanding Lead Actress in a Drama Series | Tatiana Maslany | Won | |
| 7th Critics’ Choice Television Awards | Best Lead Actress in a Drama Series | Nominated | ||
| 2017 | 21st Satellite Awards | Best Actress in a Series – Drama or Genre | ||
| Best Television Series – Genre | Orphan Black | |||
| People’s Choice Awards | Favorite Cable Sci-Fi/Fantasy TV Show | Orphan Black | Nominated | |
| Canadian Screen Awards | Best Dramatic Series | Orphan Black | Won | |
| Best Direction in a Dramatic Series | John Fawcett – Transgressive Border Crossing | Won | ||
| Best Original Music Score for a Series | Trevor Yule – “The Scandal of Altruism” | Won | ||
| Best Performance by an Actor in a Featured Supporting Role in a Dramatic Program or Series | Kevin Hanchard | Won | ||
| Best Performance by an Actress in a Continuing Leading Dramatic Role | Tatiana Maslany | Won | ||
| Best Performance in a Guest Role Dramatic Series | Gord Rand – “The Antisocialism of Sex” | Nominated | ||
| Best Photography in a Dramatic Program or Series | Aaron Morton – “From Dancing Mice to Psychopaths” | Won | ||
| Best Picture Editing in a Dramatic Program or Series | Jay Prychidny – “The Scandal of Altruism” | Won | ||
| Best Production Design or Art Direction in a Fiction Program or Series | John Dondertman, Liz Calderhead – “Human Raw Material” | Won | ||
| Best Sound in a Comedy or Dramatic Program or Series | John Laing, Dale Lennon, Tom Bjelic, Marilee Yorston, Chris Guglick, Shaun Gratto, Marco Difelice, Herwig Gayer – “The Scandal of Altruism” | Nominated | ||
| Best Visual Effects | Geoff Scott, Sarah Wormsbecher, Eric Doiron, Nathan Larouche, Anthony DeChellis, Lon Molnar – “From Dancing Mice to Psychopaths” | Nominated | ||
| Best Writing in a Dramatic Series | Russ Cochrane – “Transgressive Border Crossing” | Nominated | ||
| Aubrey Nealon – “The Stigmata of Progress” | Nominated | |||
| Graeme Manson – “The Collapse of Nature” | Won | |||
| ACTRA Awards | Outstanding Performance – Male | Gord Rand | Nominated | |
| Outstanding Performance – Series Ensemble | Nominated | |||
| GLAAD Media Award | Outstanding Drama Series | Orphan Black | Nominated | |
| Canadian Cinema Editors Awards | Best Editing in 1 Hour Scripted | Jay Prychidny – “The Scandal of Altruism” | Pending | |
| Prix Aurora Awards | Best Visual Presentation | John Fawcett and Graeme Manson | Pending |